A report on linear non threshold theory lnt by national research council

This[ edit ] This statement: Not just the bad grammar, but the entire point here makes no sense. A study advocating the linear model is ignoring evidence that the non-linear thresholded model is incorrect???

A report on linear non threshold theory lnt by national research council

Graphical Abstract

Abstract Abstract— Cancer risk estimates are used in the setting of radiation protection standards by international and national organizations, and for this purpose need to be developed for low doses of radiation.

The approach has involved extrapolation from cancer mortality and incidence values at higher doses to predict the low-dose estimates. Such an extrapolation has generally involved the use of the linear non-threshold LNT theory.

The overall conclusion from both committees was that current scientific evidence remains consistent with the LNT hypothesis, while appreciating that this might not rule out the possibility that other extrapolation models might well be valid but require further evaluation and additional research to establish their validity.

The dose and dose-rate effectiveness factor DDREF is used for adjustment in the extrapolation from high to low doses and from high to low dose rates.

Linear no-threshold model

This is a departure from the previously used value of 2, which is still proposed by ICRP in its most recent recommendations.

The major conclusion is that potential radiation risks need to be considered along with the pros and cons of the detection limits of the procedure and the impact of false positives.Although in describing LNT process both theory and hypoth- esis are used, in this paper we rely upon the most recent report of the National Research Council (NRC ) where the word hypothesis is.

A report on linear non threshold theory lnt by national research council

Such an extrapolation has generally involved the use of the linear non-threshold (LNT) theory. Recent reports from the National Research Council (BEIR VII) and the International Commission on Radiological Protection (ICRP) have considered the appropriateness of the use of LNT for the purposes of radiation protection standard setting.

Substantial research has recently shown that the NAS BEAR I Committee, Genetics Panel misrepresented the research record in its key technical publication in Science (June ) 5 that recommended the switch from threshold to LNT for risk assessment.

The Linear Non-Threshold (LNT) process is used by virtually all governmental agencies to compute incidence of cancer as a consequence of exposure to a carcinogen. Although in describing LNT process both theory and hypothesis are used, in this paper we rely upon the most recent report of the National Research Council where the word.

May 24,  · The atomic bomb survivor cancer mortality data have been used in the past to justify the use of the linear no-threshold (LNT) model for estimating the carcinogenic effects of low dose radiation. An analysis of the recently updated atomic bomb survivor cancer mortality dose-response data shows that.

The linear no-threshold model (LNT) is a model used in radiation protection to quantify radiation exposure and set regulatory limits.

It is most frequently used to calculate the probability of radiation induced cancer at both high doses where epidemiology studies support its application but, controversially, it likewise finds applications in calculating the effects of low doses, a dose region.

Linear No-Threshold Model VS. Radiation Hormesis